Our dedicated Haemato-oncology clinical trials team are an integral part of our clinical service. The clinical trial work of the team sits within The Academic Directorate of Communicable Diseases and Specialised Medicine (CDSM). All haemato-oncology consultants are involved in a large number of clinic trials as well as several consultants who sit on the relevant NCRI Haematological Oncology Sub-Groups and are actively involved in various trial management groups.

The Haemato-oncology team at Sheffield Teaching Hospitals are in the privileged position to have two clinical research teams able to deliver clinical trials in Haemato Oncology, both with a wealth of expertise. We have HO research team that work via the Sheffield Cancer Clinical Trials Centre (CCTC). The team currently consist of a team of 4 research nurses, 4 data managers and a data assistant all working on an extensive number of haemato-oncology clinical trials including early phase I and II trials. We also have a purpose-built clinical research facility (CRF) which provides an ideal environment, with consulting rooms, treatment suite and sample processing laboratory, for the assessment and treatment of patients on novel therapies. Both teams work together and alongside our clinical trials pharmacy team, the directorate research coordinator and the clinical research and innovation office.

What are clinical trials?

Clinical trials are research studies that involve people. Through clinical trials, doctors find new ways to improve treatments and the quality of life for people with disease.

Researchers design cancer clinical trials to test new ways to:


• Treat cancer
• Find and diagnose cancer
• Prevent cancer
• Manage symptoms of cancer and side effects from its treatment

Clinical trials are the final step in a long process that begins with research in a laboratory. Before any new treatment is used with people in clinical trials, researchers work for many years to understand its effects on cancer cells in the laboratory.

The advantages of taking part in a trial include that:

• You may have a treatment which is only available as part of a trial

• The new treatment may work better than the standard treatment (no one knows this for sure, which is why the trial is being done)

• You could help to improve cancer treatment for patients in the future

If you are interested in taking part in a clinical trial please speak with your clinical team in the first instance.

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